New preprint: overcoming the accuracy-generalization tradeoff in docking and scoring for prospective virtual screening. Read the paper

Resource Library

Reflections on advancing life science so we can get new drugs to market faster.

Sort by:
Event Drug discovery

Webinar: Useful Generalization is the Benchmark That Matters

Updated:
Blog Drug discovery

DODock and DOScore: Closing the Generalization Gap in Structure-Based Virtual Screening

Updated:
News Company News

Deep Origin Introduces Novel Virtual Screening Architecture; Achieves 100-fold Hit Rate Jump on Challenging Target

Updated:
Paper Drug discovery

Overcoming the accuracy-generalization tradeoff in docking and scoring for prospective virtual screening

Updated:
News Company News

Deep Origin's Computational Platform Rationalizes Results of Molecular Glue Compound That Potently Kills Diffuse Large B Cell Lymphoma Cells

Updated:
Paper Emerging science

A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death

Updated:
Press mention Company News

Michael Antonov: From Virtual World Builder to Real-World Drug Designer

Updated:
Press mention Drug discovery

Can AI Shrink the Drug Development Timelines for Endometriosis?

Updated:
News Company News

Tim Foley Joins Deep Origin as Chief Commercial Officer

Updated:
News Company News

Deep Origin Promotes Natalie Ma, PhD, to Chief Business Officer as Company Advances Computational Drug Discovery Platform

Updated:
News Company News

Deep Origin Congratulates Isomorphic Labs on Catching Up

Updated:
Blog Drug discovery

Finding Promising Molecules and Biological Background With Balto

Updated:
Blog Company News

We Built a 98% Accurate Full Molecule Data Extractor for PDFs, Now You Can Use It

Updated:
Press mention Company News

Ginkgo Bioworks partners on Deep Origin-led team to develop new tools for predicting drug safety

Updated:
News Company News

We're Leading an Up to $31.7M ARPA-H Contract Award to Build In-Silico Models To Replace Animal Testing

Updated:
Scientific poster Drug discovery

Accelerating Drug Discovery with Physics-Informed Machine Learning

Updated:
Press mention Company News

Deep Origin Partners with AccuKnox for Cloud Security

Updated:
Blog Trends

Out-of-the-Box GenAI for Medicinal Chemistry

Updated:
Blog Drug discovery

A Blind Spot in Drug Discovery: Pocket Finding

Updated:
Press mention Company News

Ashot Papoyan Advances Biotech in US and Armenia

Updated:
Paper Emerging science

Deep mutational scanning reveals EGFR mutations conferring resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945

Updated:
Press mention Company News

From Scientist to Startup Founder: Building the Virtual Cell for Drug Discovery

Updated:
Paper Emerging science

Can AI Agents Design and Implement Drug Discovery Pipelines?

Updated:
Press mention Company News

Simulating Life & Accelerating Discovery: Deep Origin's Biotech Vision | Michael Antonov (Part 4/4)

Updated:
Press mention Company News

Debugging Aging: How a VR Pioneer is Revolutionizing Longevity | Michael Antonov (Part 3/4)

Updated:
Press mention Company News

Building Oculus: Innovation, Grit & the $2 Billion VR Revolution | Michael Antonov (Part 2/4)

Updated:
Press mention Company News

The Borrowed Computer That Built Oculus - An Unlikely Biotech Journey | Michael Antonov (Part 1/4)

Updated:
Scientific poster Emerging science

Practical and Accurate Free Energy Calculations using Neural Network Potentials

Updated:
Blog Emerging science

Benchmarking and Development of AI-Based Agentic Systems for Autonomous Drug Discovery

Updated:
Event Drug discovery

Deep Origin Challenge 2025

Updated:
Press mention Company News

Why Deep Origin Is Betting on Both Physics and AI for Drug Discovery (EP 132)

Updated:
Press mention Company News

Will Oculus Co-founder Be Able To Simulate Biology Next?

Updated:
Scientific poster Emerging science

Implications of Protein Dynamics for Design of PROTACs and Molecular Glues

Updated:
Blog Trends

JPM ‘25 From the Trenches: AI in Biotech Gets Tactical

Updated:
Press mention Company News

How Biotech Will Shape Our Future on Mars and Beyond ft. Natalie Ma

Updated:
Blog Emerging science

How to Best Build a (Useful) Virtual Cell?

Updated:
Press mention Company News

Simulating Life with AI: A New Era in Biology with Michael Antonov & Natalie Ma from Deep Origin

Updated:
Blog Products

Finally, a Useful AI Assistant for Drug Discovery: Meet Balto

Updated:
News Company News

Deep Origin Launches First and Only Drug Discovery Assistant with Conversational AI Interface and Top Docking Technology

Updated:
Blog Drug discovery

Drug Discovery AI Hype and Reality: Three Scientists Go On a Hike

Updated:
Event Data analysis

Getting Your Life Science Data Ready For the AI Era

Updated:
Scientific poster Drug discovery

Discovering Novel Synthetic Lethal Pairs With Large Scale Cellular Simulations

Updated:
Press mention Products

Deep Origin's Balto AI Assistant offers bespoke drug discovery tools via a chat interface

Updated:
Scientific poster Drug discovery

Addressing Drug Discovery Challenges with a Multiscale Molecular Modeling Pipeline

Updated:
Blog Trends

AlphaFold 3: Exciting Advance yet Unresolved Major Issues Remain

Updated:
Event Drug discovery

Getting Started with Computational Drug Discovery

Updated:
Blog Drug discovery

We Spill the Beans: Deep Origin's AI- and Physics-Based Models for Drug Discovery

Updated:
Blog Drug discovery

Where Docking and Virtual Screening Can Drop the Ball in Drug Discovery

Updated:
Blog Drug discovery

Docking and Virtual Screening in Drug Discovery: Finding the Right Hit

Updated:
Event Drug discovery

Variant calling with NVIDIA Parabricks and GATK

Updated:
News Company News

Deep Origin and BiosimAI join forces in merger to accelerate R&D

Updated:
Blog Trends

From chaos to (some) order: The Life Science Software Landscape

Updated:
News Company News

Formic Labs is now Deep Origin

Updated: