Science Spotlight: Host-directed antivirals and a bivalent molecular glue

BioCentury’s Science Spotlight, written by Senior Biopharma Analyst Danielle Golovin, surveys notable recent research across two threads: a run of China-led papers on host-directed antivirals, including the small molecule MB-32 that blocks viral spike protein engagement while preserving enzymatic activity, and a bivalent molecular glue that links lysine acetyltransferases to oncogene-induced cell death.

Deep Origin is named among the companies associated with the coverage. The molecular glue work described corresponds to the transcriptional/chemical inducer of proximity approach that converts the lymphoma driver BCL6 into an activator of cell death programs. The full article is available to BioCentury subscribers.

The underlying study is available in our resource library: A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death.